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Cancer Genomics Cloud Pilots

The National Cancer Institute has funded the development of three Cancer Genomics Cloud Pilots to help meet the research community’s needs for storage, access and analysis of high quality, large-scale cancer genomic data and associated clinical information. The expectation is the development of an innovative model for computational analysis of biological data that has the potential to address current storage and analyses challenges. The project has the potential to democratize access to NCI-generated genomic data and provide a more cost-effective way to provide computational support to the cancer research community.


The National Cancer Institute has launched the NCIP Hub to help accelerate innovation in the cancer research community. It is an environment for scientific collaboration where researchers can access a variety of resources shared by other cancer researchers. The NCIP Hub is intended to support a community of members with a shared goal of democratizing access to data, tools, and standards across the cancer research community. Content contributions come from community members and can include seminar presentations, publications, training materials, data, tools, and bookmarks to useful sites and information, as well as discussions on them. Join the NCIP Hub and get started.

The NCIP Open-Development Initiative


The NCI Wiki hosts individual wikis that document the development of applications, activities of working groups, collaborations, informatics projects, and work in specific domains. Visit the wiki dashboard and select the New Account link to participate. For more information, contact Application Support.


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  • The National Coordination Office, Networking and Information Technology Research and Development (NITRD) Program issued a Request for Information seeking input from big-data stakeholders to inform the development of a framework of high-level priorities and a strategic plan for the National Big Data Research and Development Initiative. The deadline for submissions is November 14, 2014.
  • NCI has announced an exploratory study (NCT02243592) as part of the Exceptional Responders Initiative in which DNA and RNA sequencing, as well as other characterization methods, will be used to identify molecular features associated with unexpectedly positive treatment responses observed in cancer patients. Data will be shared with the research community via a controlled-access database. Co-lead investigators in the NCI Division of Cancer Treatment and Diagnosis and Center for Cancer Genomics are directing the study.
  • National Cancer Informatics Program hub building a community to accelerate cancer research, discovery
  • Following the successful completion of a three-year pilot, NIH has awarded $64 million to establish six Data and Signature Generating Centers where scientists will catalog and analyze cellular function and molecular activity in response to specific perturbations, including new therapeutic compounds under investigation. The data they produce will be collected in a database, the Library of Integrated Network-based Cellular Signatures (LINCS), that will be freely available to researchers. NIH News Release
  • NIH has issued the final version of its new policy on genomic data sharing. It will apply to all NIH-funded, large-scale human and non-human projects that generate genomic data, including research conducted with the support of NIH grants and contracts and within the NIH Intramural Research Program.

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The NCI Biomedical Informatics Blog

The NCI Biomedical Informatics Blog provides a forum for the exploration of ideas and knowledge sharing across the NCI and throughout the wider biomedical-informatics and cancer-research community.

Topics recently under discussion include potential NCI Cancer Knowledge Clouds; NCIP support for open, community-driven software development; and intramural collaborations being pursued by NCIP staff. For a more complete description, scroll through the running list of topics contained in the left navigation bar.


Recently published articles authored by NCIP staff and members of the community include the following:

Other publications are available in the Bibliography section of the NCIP website.